| Abstract |
: |
Two simple, sensitive, accurate, rapid spectrophotometric methods have been developed for the estimation of Ornidazole in parentaral dosage forms. Method A is based on the reaction of Ornidazole with PDAB, in presence of zinc dust and acidic environment, giving a orange color chromogen, which shows maximum absorbance at 390 nm against reagent blank, while method B is based on the reaction with Bromo phenol blue, in zinc dust and acidic environment absorbance at 430 nm. Beer’s law was obeyed in the concentration range of 25-162.5 µg/ml in method A, and 5-20 µg/ml in method B. Results of the analysis were validated statistically and by recovery studies. |
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