ISSN : 0975-9492


Open Access

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Title : Assessment of pharmacotherapy pattern in metabolic syndrome
Authors : Anum Sultana, V Preethi Sharon, Venkatesh Prasanna, NK Meera, Pavankumar P Rasalkar
Keywords : Cardiovascular disease (CVD), International diabetes federation (IDF), metabolic syndrome (MetS), pharmacotherapy.
Issue Date : Feb 2021
Abstract :
BACKGROUND: According to International diabetes federation (IDF), Metabolic Syndrome (MetS) is a cluster of the most dangerous cardio vascular risk factors of abdominal obesity, elevated blood glucose level, elevated blood pressure and dyslipidemia. PURPOSE: The main objective of this study was to assess the pharmacotherapy management and also to identify and report any drug-drug interactions from the treatment charts. MATERIALS AND METHOD: A 6 months prospective study was carried out in 156 patients of either gender between the age group 18 to 70 years attending the cardiology department of a tertiary care hospital. The demographic, diagnosis, pharmacotherapy data were documented and analyzed for pharmacotherapy pattern and drug-drug interactions. RESULTS AND DISCUSSION: The occurrence of MetS was higher in males (61.54%) than in females (38.46%). The maximum number of patients were between the age group 51 to 70 years. The anthropometric values (waist circumference, height, weight and BMI) were comparatively higher in males than in females whereas clinical parameters (systolic, diastolic blood pressure, fasting blood glucose, serum triglycerides and HDL) showed no significant differences between the genders. Pharmacotherapy assessment showed prescribing of anti-hypertensives greater than anti-diabetics and anti-dyslipidemics. Most of the drug interactions assessed were potential, moderate in severity, 46.56% and 41.3% from risk categories B and C respectively. CONCLUSION: A rational, systematic approach of pharmacotherapy of morbid conditions is most essential in management of patients with MetS for their overall health related quality of life.
Page(s) : 54-59
ISSN : 0975-9492
Source : Vol. 12, No.02
PDF : Download
DOI : 10.21817/ijpsr/2021/v12i02/211202013