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ABSTRACT
| Title |
: |
IN VITRO ANTIPLASMODIAL POTENTIAL OF CRUDE ALKALOIDS FROM SOME WEST AFRICAN ANTIMALARIAL PLANTS |
| Authors |
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Yusuf Hassan, Huzaifa Zaid Umar, Zaruku Abdulkadir, Hauwau Shehu Ahmad, Fatima Salman Ibrahim, Ibrahim Nalado Ahmad, Hafiz Tasiu Ahmad |
| Keywords |
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Crude alkaloids, Antimalarial plants, West Africa, Antiplasmodial activity, Plasmodium falciparum |
| Issue Date |
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Jul 2020 |
| Abstract |
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Crude alkaloids of various quantities were extracted from the leaves, stem barks, and roots of twelve plants widely used in West Africa for the treatment of malaria. The samples were evaluated for antiplasmodial activity at four different concentrations, and the percentage elimination of the parasitemia after the incubation period was calculated. It was found that the crude alkaloids from the leaves of Daniellia oliveri and Parkia biglobosa demonstrated the highest elimination percentage (79%) albeit lower than the standard drug (artemether-lumefantrine) which had 94% elimination ability. |
| Page(s) |
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188-191 |
| ISSN |
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0975-9492 |
| Source |
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Vol. 11, No.07 |
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