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ABSTRACT
| Title |
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HPLC method for determination of dimetindene maleate in pharmaceutical preparations and environmental water samples: Application to content uniformity testing |
| Authors |
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Nief Rahman Ahmed |
| Keywords |
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Dimetindenemaleate, determination,HPLC, pharmaceuticals. environmental water samples |
| Issue Date |
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Jul 2019 |
| Abstract |
: |
Arapid assay method based on high performance liquid chromatography (HPLC) have been developed for the determination of dimetindene maleate in pharmaceutical formulations and environmental water samples. The HPLC determination was carried out on a reversed phase C18 column using acetate buffer pH(4.0): Acetonitrile as mobile phase (65:35), at a flow rate1.0 ml.min-1 with UV-detection at 254 nm. A recti lines relationship was observed between 2.0-7.0 µg.ml-1dimetindene maleate. The proposed method have been successfully applied to the determination of dimetindene maleate in various dosagepharmaceuticals forms and environmental water samples |
| Page(s) |
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195-199 |
| ISSN |
: |
0975-9492 |
| Source |
: |
Vol. 10, No.7 |
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