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ABSTRACT
| Title |
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IDENTIFICATION, QUNATITATIVE DETERMINATION&ANTIDEPRESSANT ACTIVITY OF CHLOROGENIC ACID& GALLIC ACIDFROM MORUS ALBA LEAVES |
| Authors |
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Shiv Bhadra Singh, Meraj Ali, Aaditya Singh |
| Keywords |
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- |
| Issue Date |
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May 2019 |
| Abstract |
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Objective: The present study is considered to estimate preliminary phytochemical components,physicochemical parameters, HPTLC chromatographic studies and antidepressant activity of chlorogenic acid &gallic acid present in extracts ofmorusalba leaves. Methods:Total phenol content, Total flavonoid content, Total tannin content, HPTLC fingerprinting analysis for compounds likechlorogenic acid &gallic acidresponsible for antioxidant activity and antidepressant activity by TST & FST. Result:Preliminary phytochemical studies shows the presence of good phenol (21.75 ± 1.21) and flavonoid (14.83 ± 2.34) content. HPTLC fingerprinting by comparing extract values with standards available of chlorogenic acid &gallic acid also shows the presence of these components in the methanolic and ethanolic extracts of morusalba leaves, which were further used to screen antidepressant activity and shows substantial antidepressant activity in the plant. Conclusion:Our results recommends that morusalba leaves are may be demonstrated to be anacceptable natural antioxidant and antidepressant with various bioactive components used for the treatment of numerous other ailments. |
| Page(s) |
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140-147 |
| ISSN |
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0975-9492 |
| Source |
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Vol. 10, No.5 |
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