ISSN : 0975-9492
CODEN : IJPSQQ





INTERNATIONAL JOURNAL OF PHARMA SCIENCES AND RESEARCH


Open Access

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ABSTRACT

Title : SYNTHESIS AND CHARACTERIZATION OF CHLORAMPHENICOL SILVER NANOSHELLS FOR TARGETING DIVERSE BACTERIAL INFECTIONS
Authors : V.Viswanath, G.CharankumarReddy, C.Rupa, A.SaiPavan, K.HannaPravallika, D. Bhanu Priya
Keywords : Silver nanoshells, chloramphenicol, antibacterial, nanoparticles.
Issue Date : Apr 2019
Abstract :
Nanoparticles offer the possibilities of being used in the treatment of various diseases. Although the synthesis of nanoshells is quite complicated, they exhibit a marked significance in eliciting the required therapeutic activity. The synthesis of silver nanoshells proceedinitially through generation of dielectric core containing chloramphenicol and simultaneous generation of nanoshells by altering the concentrations of Ethanol and Tetraethoxysilane (TEOS). Therefore, 5 varied formulations of chloramphenicol silver nanoshells are generated and the resultant are subjected to various characterization techniques such as drug content, entrapment efficacy, particle size, surface morphology, X-Ray diffraction, HRTEM etc. The results reveal that F1 meets the required criteria and are quite suitable for commercialization and serve as a basis for targeted drug delivery system.
Page(s) : 120-132
ISSN : 0975-9492
Source : Vol. 10, No.4