ISSN : 0975-9492


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Title : In Vitro Assessment of Terminalia chebula Retz. Fruits Against Methicillin Resistant Staphylococcus aureus
Authors : M. Revathi, G. Senthilkumar, A. Panneerselvam, E.S. Karthy, R. Gopika
Keywords : Methicillin resistant Staphylococcus aureus (MRSA); Terminalia chebula; Antibacterial activity; Minimum Inhibitory Concentration (MIC); Phytochemical.
Issue Date : Nov 2016
Abstract :
Terminalia chebula is a popular medicinal plant according to Ayurveda for its broad spectrum medicinal value including in the treatment of wound healing. Fruit extracts in aqueous as well as in various solvents like Acetone, Ethanol and Methanol were analyzed to testing its antibacterial activity against 16 Methicillin Resistant Staphylococcus aureus (MRSA). The analysis was carried out by taking the extracts at a concentration of 500mg/ml and their activities were recorded by zone of inhibition as produced by disc diffusion method. Maximum zone was observed (20 to 25mm) in all the tested extracts, in microdilution assay revealed that the bactericidal values for in the range of 0.24 to 7.81mg/ml. Phyto-chemical analysis of Terminalia chebula extracts showed the presence of secondary metabolites like Alkaloid, Flavonoid, Terpenoid and Tannin. The chromatography analysis has revealed the presence of Aminoacid, Phenolic compound and aromatic compound as functional groups in Terminalia chebula. These findings indicate that the Terminalia chebula possesses a potential antibacterial activity against MRSA.
Page(s) : 465-470
ISSN : 0975-9492
Source : Vol. 7, No.11