ISSN : 0975-9492


Open Access

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Title : Quantitative Estimation of Ciprofloxacin and Tinidazole of Marketed Preparation using Hydrotropic agent
Authors : Suman Gehlot, Debadash Panigrahi, Raghvendra Dubey
Keywords : Ciprofloxacine, Tinidazole, Urea
Issue Date : Nov 2016
Abstract :
The proposed method is new, simple, environmentally friendly, accurate, reproducible, precise and validated statistically for quantitative estimation ciprofloxacin and tinidazole in tablet dosage form The % of drug content by absorption ratio method of CFC and TIN in tablet dosage form was found to be with in the range of 99.70-100.30 % and 99.75-100.50% respectively. The result of recovery study shows that the % of recovery for both the drugs were with in the range of 99 100%. Precision study shows that the drug content for both drug in market formulation were within the range of 97 - 101%. In derivative spectroscopy method, the % of drug content in tablet dosage form was within the range of 99.98-100.20% and 99.86-100.08% for CFC and TIN respectively. The % of drug content of both drugs in recovery and precision study for tablet dosage form were with in the range of 98 -102%and 98- 101% respectively.
Page(s) : 440-447
ISSN : 0975-9492
Source : Vol. 7, No.11