ISSN : 0975-9492


Open Access

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Title : Antibacterial behaviour of root extracts of Tragia involucrata L. in gradient extraction
Authors : Toji Thomas
Keywords : Tragia involucrata; Euphorbiaceae; Antibacterial; disc diffusion; MIC
Issue Date : Nov 2016
Abstract :
Tragia involucrata has been widely used for treating different diseases in ancient systems of medication. Tribal people use the plant root in controlling skin infections and asthma. In the this study, roots of Tragia involucrata checked for antibacterial nature and the occupancy of phytochemical constituents in discrete solvent extracts in accelerating polarity with respect to disease producing bacterial species implicated in skin diseases in human beings. Antibacterial activity tested by disc diffusion method. The results pointed out that the roots showed antibacterial power mainly in acetone extract. Petroleum ether and water extracts could not present a little antibacterial ability towards all of the tested organisms. As the extraction proceeded from non-polar to polar solvents, gradual reduction in activity was noticed. Phytochemical analysis indicated that phenolics and flavonoids were predominant in acetone extracts. Presence of phenols and flavonoids in acetone decoction can be considered as one of the judgements for antibacterial potential of roots Tragia involucrata. Acetone extract of roots of the plant manifested minimum inhibitory concentration around 50mg/ml. Acetone extract of roots of the plant demonstrated minimum bactericidal concentration at the rate of 100mg/ml with respect to Pseudomonas aerugenosa.
Page(s) : 419-422
ISSN : 0975-9492
Source : Vol. 7, No.11