ISSN : 0975-9492
CODEN : IJPSQQ





INTERNATIONAL JOURNAL OF PHARMA SCIENCES AND RESEARCH


Open Access

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ABSTRACT

Title : In vitro antioxidant and cytotoxic activity of ethanolic extract of Cinnamomum tamala (Tejpat) leaves
Authors : Salma Akter, Md. Ashraf Ali, Ranjan Kumar Barman, Bytul Mokaddesur Rahman, Mir Imam Ibne Wahed
Keywords : Cinnamomum tamala (CT); DPPH radical; Brine shrimp; Antioxidant activity and Cytotoxic activity.
Issue Date : March 2015
Abstract :
The present research was aimed to investigate in vitro antioxidant and cytotoxic effects of the ethanolic extract of the leaves of Cinnamomum tamala (Nees). The leaves of Cinnamomum tamala have shown good antioxidant and cytotoxic properties. Antioxidant activity of the extract was evaluated by using DPPH free radical scavenging assay and ascorbic acid used as a standard. The IC50 value of Cinnamomum tamala leaves was 13.55 g/ml while the IC50 value of ascorbic acid was 5.35 g/ml. Cytotoxic activity was evaluated by using brine shrimp lethality bioassay and vincristine sulphate used as a standard. In this assay, the LC50 value of the ethanolic extract of Cinnamomum tamala leaves was 17.82g/ml whereas LC50 value of vincristine sulphate was 5.24g/ml. Therefore, these results suggest that leaves extract of Cinnamomum tamala has antioxidant and cytotoxic activities.
Page(s) : 532-536
ISSN : 0975-9492
Source : Vol. 6, No.3