ISSN : 0975-9492
CODEN : IJPSQQ





INTERNATIONAL JOURNAL OF PHARMA SCIENCES AND RESEARCH


Open Access

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ABSTRACT

Title : In-Vitro Cytotoxic and Thrombolytic Potential of Methanolic Extract of Podocarpus neriifolius D. Don leaves
Authors : Zaman Rashaduz, Parvez Mohammed, Jakaria Md, Sayeed Mohammed Abu
Keywords : Brine shrimp, Thrombolytic, Cytotoxic, Clot lysis, Podocarpus neriifolius.
Issue Date : February 2015
Abstract :
The present study was aim to evaluate the cytotoxic activity by in-vitro brine shrimp lethality bioassay and thrombolytic potentials of methanolic extract of leaves of Podocarpus neriifolius. In brine shrimp bioassay, the crude methanolic extract of leaf showed strong cytotoxic activity with LC value of 18.24g/ml compared to that of 0.839 g/ml exhibited by standard vincristine sulphate. It has significant thrombolytic activity (44.82%) compared to standard streptokinase (77.66%). The results of this study confirm that this plant will be good candidate for future research of anticancer and thrombolytic drugs.
Page(s) : 273-277
ISSN : 0975-9492
Source : Vol. 6, No.2