ISSN : 0975-9492


Open Access

This website is certified by Health On the Net Foundation. Click to verify.

This site complies with the HONcode standard for trustworthy health information:
verify here.


Title : Steroidogenetic and Spermatogenetic Activities of Aqueous Extract of Phragmanthera capitata in Wistar Rats
Authors : Lapah Pièrre Takem, Ching Fidelis Poh, Eban Linus Kechi, Noa Pièrre Abe
Keywords : Phragmanthera capitata, steroidogenesis, spermatogenesis, loranthaceae, sired litters.
Issue Date : October 2014
Abstract :
This study was carried out to investigate steroidogenetic and spermatogenetic activities of aqueous extract of Phragmanthera capitata (AEPC) in male Wistar rats. Healthy adult male Wistar rats of proven fertility weighing 150-200 g were randomized into three groups with body weights measured weekly. Group I (control) received 10 ml/kg saline, Groups II and III (tests) received 150 and 300 mg/kg AEPC respectively per oral per day for 60 days. Mating test was assessed from day 55 with cohabitation with coeval females for 5 days with the resulting sired litters counted and pup weights measured. The males were sacrificed; testes, epididymis, seminal vesicles and ventral prostrate were excised and weighed. Epididymal sperm motility (EPM), epididymal sperm reserve (ESR), daily sperm production (DSP), blood testosterone and cholesterol concentrations were measured. Mean weekly body weight as well as weights of testes, epididymis, seminal vesicles and ventral prostate revealed no significant change as compared to control. Similarly, no significant changes in EPM, ESR and DSP in test groups were observed. However, cholesterol and testosterone levels were significantly (P <0.05) increased while mating test showed a corresponding significant (P <0.05) increase in pup weight of 28.85±0.76 for 300 mg/kg AEPC as compared to 20.53±0.52 for control. Therefore, AEPC enhances steroidogenetic and spermatogenetic activities in male Wistar rats.
Page(s) : 609-614
ISSN : 0975-9492
Source : Vol. 5, No.10