ISSN : 0975-9492
CODEN : IJPSQQ





INTERNATIONAL JOURNAL OF PHARMA SCIENCES AND RESEARCH


Open Access

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ABSTRACT

Title : Study on antibacterial and antioxidant activity of Berberis vulgaris aqueous extracts from Iran
Authors : Zahra dashti, Nabi shariatifar, Abdolreza Mohammadi Nafchi
Keywords : Aqueous extract, Berberis vulgaris, Antioxidant activity, anti bacterial activity.
Issue Date : October 2014
Abstract :
The antioxidant and antibacterial are group from food additive that use on food as preservative. The objective of this study was to determine antioxidant and antibacterial activity of Berberis vulgaris fruit the using different in vitro methodologies. The aquatic and ethanolic extracts, at a concentration from 35to 40 g/ml, showed a significant antibacterial effect expressed as minimum inhibitory concentration (MIC) against both Gram-negative and Gram-positive bacteria. In particular, Pseudomonas aeruginosa (MIC=16 microg/ml), Proteus vulgaris (MIC=32 microg/ml) and Escherichia coli (MIC=32 microg/ml) were the most inhibited. The antioxidant activity were determined by the 2,2-diphenylpicrylhydrazyl (DPPH) assay and a -carotene bleaching assay, and compared with that of butylated hydroxyl toluene (BHT). The data were expressed as the mean the standard deviation and they were statistically analyzed by SPSS software using ANOVA (P<0.05).
Results: The results showed that among all the solvent extracts, water extractof Berberis vulgaris friut had high antioxidant activities as measured by DPPH scavenging (28.620.01, 20.580.12 and 50.780.17, 142.91.12, 56.082.72, 120.430.85 g/ml) and inhibition of linoleic cid oxidation, respectively (77, 86,70, 58, 72, 62%). These parameters for BHT were 100.02 g/ml, and 95.24%0.14.
Conclusion: The findings indicated that the water extracts of Berberis vulgaris friut can act both as natural antioxidants and antibacterial and as a possible food supplement or be used in pharmaceutical industry after complementary tests.
Page(s) : 705-708
ISSN : 0975-9492
Source : Vol. 5, No.10