ISSN : 0975-9492
CODEN : IJPSQQ





INTERNATIONAL JOURNAL OF PHARMA SCIENCES AND RESEARCH


Open Access

This website is certified by Health On the Net Foundation. Click to verify.

This site complies with the HONcode standard for trustworthy health information:
verify here.

ABSTRACT

Title : Method development and validation of Vildagliptin using UV spectrophotometer
Authors : Dr. Safila Naveed, Hina Rehman, Fatima Qamar, Syeda Zainab
Keywords : Vildagliptin, accuracy, linearity, regression equation , precision.
Issue Date : October 2014
Abstract :
Vildagliptin is an antidiabetic agent, belongs to the dipeptidyl peptidase IV (DPP-4) inhibitors. The method employs measurement of absorbance at the wavelength of maximum absorptions of vildagliptin using water as a solvent. Calibration curve was linear in the concentration range of 12.5-200 microgram per ml g/ml for vildagliptin with the correlation coefficient of 0.985. Accuracy of proposed method was confirmed by performing accuracy studies which showed the results within the range. Precision of proposed UV method was confirmed by performing intraday and inter day precision. Results were well within acceptance criteria which indicate the method has excellent scope for the determination of Vildagliptin in bulk.
Page(s) : 714-717
ISSN : 0975-9492
Source : Vol. 5, No.10