ISSN : 0975-9492
CODEN : IJPSQQ





INTERNATIONAL JOURNAL OF PHARMA SCIENCES AND RESEARCH


Open Access

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ABSTRACT

Title : Analysis Of Phytochemical Constituents And Antimicrobial Activities Of Alpinia calcarata Against Clinical Pathogens
Authors : Jency George
Keywords : Antimicrobial activity, GC/MS, Phytochemistry, Alpinia calcarata
Issue Date : September 2014
Abstract :
To study the antimicrobial activity and phytochemical characterization of essential oil isolated from the rhizome of Alpinia calcarata against pathogenic bacteria and fungi. Fresh rhizomes of Alpinia calcarata were subjected to hydro distillation process to obtain essential oil and characterized by Gas Chromatography- Mass Spectroscopy (GC-MS). The essential oil was evaluated for antibacterial and antifungal activity against ten pathogenic bacteria and seven fungi by the disc diffusion method. GC MS analysis of the essential oil extracted from the rhizome of Alpinia calcarata contained the derivatives of 2-octanone, camphene, 1,8-cineole, a fenchyl acetate, 2 hexanone, 4 methyl- 2- hexanone and other minor compounds. The antimicrobial activity of the oil showed significant inhibitory activity against the human pathogenic bacteria, no activity was observed against the fungi Aspergillus aculeatus and Fusarium oxysporum. The findings of the present study indicate that the rhizome extract of Alpinia calcarata possess secondary metabolites and potential to develop antimicrobial drugs.
Page(s) : 555-560
ISSN : 0975-9492
Source : Vol. 5, No.9