ISSN : 0975-9492
CODEN : IJPSQQ





INTERNATIONAL JOURNAL OF PHARMA SCIENCES AND RESEARCH


Open Access

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ABSTRACT

Title : In-vitro potential antimicrobial and antioxidant activities of Lablab niger leaves
Authors : Md. Reyad-ul-Ferdous, Mosharaf Hossen, Fazle Noor Biswas
Keywords : Lablab niger; antimicrobial activity; DPPH; total phenolic content.
Issue Date : June 2014
Abstract :
Purpose: In this studies investigate potential in-vitro antimicrobial activity as well as antioxidant activities of methanol extracts and different fractions of Lablab niger leaves. Methods: The carbon tetrachloride and chloroform soluble fractions exhibited significant antibacterial activity, whereas methanolic extract and pet-ether soluble fractions showed mild to moderate antimicrobial activity against the tested microorganisms. Results: Total phenolic content (expressed as gallic acid equivalent) ranged from 5.65 to 75.91 mg per gm of dried extract. In DPPH free radicals assay, carbon tetrachloride (CTCSF) and aqueous soluble fractions (AQSF) exhibited significant free radical scavenging activity with IC50 value of 6.67 g/ml and 6.73 g/ml, respectively. Conclusions: These finding for the first time indicate that L. niger leaves could be an vital sources of natural antimicrobial and antioxidant activities.
Page(s) : 257-261
ISSN : 0975-9492
Source : Vol. 5, No.6