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ABSTRACT
| Title |
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Formulation and evaluation of ciprofloxacin suspension using natural suspending agent |
| Authors |
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Sameer J. Nadaf, Sachin S. Mali, Sachin S. Salunkhe, Piyush M. Kamble |
| Keywords |
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Ciprofloxacin, Suspension, Sedimentation volume, redispersibility, flocculation |
| Issue Date |
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March 2014 |
| Abstract |
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The aim of the present study is to formulate and evaluate ciprofloxacin suspension using natural suspending agent. Trigonella foenum graecum Mucilage was used as natural suspending agent. Total 9 batches (C1-C9) were prepared by varying concentration of suspending agent from 0.5-2% and propylene glycol. Prepared suspension were evaluated by studying different parameters like pH, sedimentation volume, redispersibility, Flow rate (F), viscosity, degree of flocculation, effect of temperature etc. batches C6, C7 and C8 were found to be stable throughout the study. As the concentration of suspending agent increased viscosity also get increased which reduces the sedimentation and contributes to the stability of suspension. Increase in viscosity avoids the particle aggregation so particles remain in a flocculated state. |
| Page(s) |
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63-70 |
| ISSN |
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0975-9492 |
| Source |
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Vol. 5, No.3 |
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