ISSN : 0975-9492
CODEN : IJPSQQ





INTERNATIONAL JOURNAL OF PHARMA SCIENCES AND RESEARCH


Open Access

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ABSTRACT

Title : Synthesis, Characterization and antimicrobial activity of Cyanopyridine derivatives with Vanillin.
Authors : V. R. Dangar, K. N. Borkhataria, V. R. Shah
Keywords : Chalcone, cyanopyridine, antimicrobial activities.
Issue Date : February 2014
Abstract :
Cyanopyridines play a vital role owing to their range of biological and physiological activities. In the light of these biological activities and variety of industrial applications, some new of 6-Aryl-4-[4-(p-chlorobenzyloxy)-3-methoxyphenyl]-2-methoxy-3-cyanopyridines (1a-l) & 6-Aryl-4-[4-(p-chlorobenzyloxy)-3-methoxyphenyl]-2-ethoxy-3-cyanopyridine (2a-l) have been prepared, by the cyclocondensation of 1-Aryl-3-[4-(p-chlorobenzyloxy)-3-methoxyphenyl]-propenones type (I) with malononitrile in presence of Sodiummethoxide & Sodiumethoxide. All the prepared compounds were characterized by their spectral (I.R., N.M.R. ,Mass) data and screened for their antimicrobial activities.
Page(s) : 20-24
ISSN : 0975-9492
Source : Vol. 5, No.2