ISSN : 0975-9492
CODEN : IJPSQQ





INTERNATIONAL JOURNAL OF PHARMA SCIENCES AND RESEARCH


Open Access

This website is certified by Health On the Net Foundation. Click to verify.

This site complies with the HONcode standard for trustworthy health information:
verify here.

ABSTRACT

Title : EVALUATION OF ANALGESIC AND ANTIMICROBIAL ACTIVITY OF DIFFERENT FRACTIONS OF CRUDE METHANOL EXTRACT OF TINOSPORA CRISPA STEM.
Authors : Md. Ariful Islam, Mohammad Ruhul Amin, Zobaer Al Mahmud
Keywords : Analgesic, antibacterial, antifungal, Tinospora crispa, Menispermaceae.
Issue Date : January 2014
Abstract :
Tinospora crispa, a plant belonging to the family of Menispermaceae is a well-known traditional medicinal plant used in Bangladesh. This study has carried out to evaluate the analgesic (by acetic acid induced writhing test) activities by using Swiss albino mice as a test animal. At a dose of 400 mg/kg body weight, the crude methanol extract and its other fractions of stem significantly (p<0.05) produced inhibition of writhing compared to the Standard (Diclofenac Sodium). Among all the fractions, Petroleum ether soluble fraction showed most significant analgesic activity (51.94%) compare with standard (65.12%). In addition the crude extract and its fraction showed no significant antimicrobial activities against five gram-positive, eight gram-negative bacteria and three fungi compare to the standard (kanamycin).
Page(s) : 16-21
ISSN : 0975-9492
Source : Vol. 5, No.1