ISSN : 0975-9492
CODEN : IJPSQQ





INTERNATIONAL JOURNAL OF PHARMA SCIENCES AND RESEARCH


Open Access

This website is certified by Health On the Net Foundation. Click to verify.

This site complies with the HONcode standard for trustworthy health information:
verify here.

ABSTRACT

Title : LIQUID-LIQUID EXTRACTION AND SPECTROPHOTOMETRIC DETERMINATION OF IRON USING ACETOPHENONE 2’,5’-DIHYDROXY THIOSEMICARBAZONE (ADHTS) AS A NEW ANALYTICAL REAGENT
Authors : Prabhakar S. Navarkar, Rama S. Lokhande, Shirish M. Pitale, Suhas P. Janwadkar, Paritosh K. Rana, Dilip K. Yadav
Keywords : Iron, Spectrophotometric determination, n-Butanol, Acetophenone 2’, 5’- dihydroxy thiosemicarbazone derivative
Issue Date : September 2012
Abstract :
Acetophenone 2’,5’-dihydroxy thiosemicarbazone (ADHTS) is proposed as a new sensitive and selective reagent for the Spectrophotometric determination of trace amount of Iron. The optimum extraction conditions were evaluated by studying various parameters like pH, solvent, reagent concentration, equilibration time and stability of extracted complex. The reagent reacts with Iron to form a yellow colored 1:2 chelate, at the pH 3.6.The complex is extracted in n-Butanol. The absorption spectrum shows maxima at 430 nm. Beer’s law is obeyed in the concentration range 1 to 8 ppm for Iron. The molar absorptivity is 646.06 L mol-1cm–1 and Sandell’s sensitivity is 0.0869µg cm-2 The Limit of Detection for the proposed method was found to be 0.561 ppm. The proposed method is highly sensitive, selective, simple, rapid, accurate, and has been satisfactorily applied for the determination of Iron in the synthetic mixtures, and real samples.
Page(s) : 459-462
ISSN : 0975-9492
Source : Vol. 3, No.9