ISSN : 0975-9492
CODEN : IJPSQQ





INTERNATIONAL JOURNAL OF PHARMA SCIENCES AND RESEARCH


Open Access

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ABSTRACT

Title : TO INVESTIGATE THE ACTION OF GINGER-JUICE ZINGIBER OFFICINALE ROSCOE (ZINGIBERACEAE) ON BLOOD COAGULATION PROCESS
Authors : S.S.Prasad, Sushil Kumar, Kamlesh Patel, Chandresh Dumater, S.K.Vajpeyee, V.H. Bhavsar
Keywords : Ginger-juice (G.J), blood coagulation, BT, CT, prothrombin time, thrombin time, PTTk, platelet count.
Issue Date : July 2012
Abstract :
Investigation of ginger-juice (zingiber officinale roscoe) action on blood coagulation process in rat. Methods: (A) Albino Wister rats (n=6-12) were administered G.J at two doses (2ml & 4 ml/rat, p.o) as single administration and chronic treatment over period of 30 days. Following this assessment was done for possible effects on the blood coagulation. Parameters used during assessment were on the bleeding time, clotting time. prothrombin time, thrombin time, partial thromboplastin with kaolin (PTTk) and platelet count. Results: Chronic administration of G.J (2ml & 4ml/rat, p.o) caused an increase in the bleeding time. There is no effect of gingerjuice treatment (2ml & 4ml/rat, p.o) for 30 days on the clotting time, prothrombin time, thrombin time, partial thromboplastin time with kaolin (PTTk), and Platelet counts. Conclusion: Ginger administration increased bleeding time on chronic administration G.J in two different doses.
Page(s) : 407-415
ISSN : 0975-9492
Source : Vol. 3, No.7