ISSN : 0975-9492
CODEN : IJPSQQ





INTERNATIONAL JOURNAL OF PHARMA SCIENCES AND RESEARCH


Open Access

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ABSTRACT

Title : PHYTOCHEMICAL SCREENING AND MICROBICIDAL ACTIVITY OF STEM BARK OF PTEROCARPUS MARSUPIUM
Authors : Udaysing Hari Patil, Dattatraya. K. Gaikwad
Keywords : Bactericidal potential, Pterocarpus marsupium, phytochemical analysis, percent extract yield and phytoconstituents.
Issue Date : January 2011
Abstract :
Bactericidal potential of methanolic extract of stem bark (Apical bark, middle bark and Mature bark) of Pterocarpus marsupium was evaluated with respect to pathogenic bacteria Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoneae, Salmonella typhi, Proteus mirabilis and Micrococcus sp. The methanolic extract of apical stem bark was effective than the middle bark and mature bark in inhibiting the growth of all bacteria. The bacterium Staphylococcus aureus was most sensitive among all the bacterial species studied. Preliminary phytochemical analysis revealed the presence of alkaloids, glycosides, flavonoids, flavonols, phenols and terpenoids. Saponins were absent in all the bark samples.The concentrations of these phytoconstituents was higher in the apical stem bark than the middle and mature stem bark. The percent extract yield was maximum in apical stem bark. Thus, in the pharmacological point of view, it is important to study the biochemistry of apical bark in order to isolate and screen the new pharmacological active principals which can be useful in designing of new drugs active against various infectious micro-organisms like bacteria, fungi and viruses etc.
Page(s) : 36-40
ISSN : 0975-9492
Source : Vol. 2, No.1