Abstract |
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Stress is very common and affects as many as one in eight every people in their teen years. Depression, which is common form of stress related disorder affects people of every color, race, economic status, or age. However, it does seem to affect more females than males during adolescence and adulthood. Stress affects mind, body, and behavior in many ways. The signs and symptoms of stress vary from person to person, but all have the potential to harm our health, emotional wellbeing, and relationships with others. The stress response of the body is meant to protect and support us in maintaining stability. Our body is constantly adjusting to its surroundings. When a physical or mental event threatens this equilibrium, we react to it. Anxiety is characterized by a persistent and disproportionate fear unrelated to any genuine risk. It can increase to an extent that may interfere with even normal routine of life and person may feel apprehensive regarding happenings of normal things in life. The present paper discusses anti-anxiety potential of 15 anxiolytics with emphasis on their pre-clinical and clinical reports.majority of drugs have been found to be acting through modulation of serotonin and gamma butyric acid (GABA) neurotransmitters. |