ISSN : 0975-9492
CODEN : IJPSQQ





INTERNATIONAL JOURNAL OF PHARMA SCIENCES AND RESEARCH


Open Access

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ABSTRACT

Title : Evaluation of Antibacterial Activity of Various Extracts of Whole Plant of Borreria hispida (Linn)
Authors : A.Kottai Muthu, Penugonda Sravanthi, D.Satheesh Kumar, A. Anton smith, R. Manavalan
Keywords : Whole plant of Borreria hispida, antibacterial activity, hot continuous percolation.
Issue Date : March 2010
Abstract :
The objective of this study was to evaluate the antibacterial activity of various extracts of whole plant of Borreria hispida (Linn). The extract was prepared from the whole plant of Borreria hispida by hot continuous percolation method in Soxhlet apparatus with various solvents (Pet. Ether, ethyl acetate, Methanol). All the extracts of Borreria hispida were tested for antibacterial efficacy against Bacillus subtilis NCIM 2063, Bacillus pumilus NCIM 2327, Staphylococcus aureus NCIM 2079, Pseudomonas aeruginosa NCIM 2036, Escheria coli NCIM 2065, Klebsiella pneumonia NCIM 2957. All the three extracts were comparable with standard drug (Ciprofloxacin). The methanolic extract was found to be the most effective anti bacterial activity against the entire organism tested. The minimum Inhibitory concentration of methanolic extract of Borreria hispida was found to the range 250 mcg/ml to 50 mg/ml on tested all the test organisms. This study scientifically supports the usage of whole plant as a remedy for various superficial bacterial and fungal infections in traditional medicine.
Page(s) : 127-130
ISSN : 0975-9492
Source : Vol. 1, No.2