ISSN : 0975-9492
CODEN : IJPSQQ





INTERNATIONAL JOURNAL OF PHARMA SCIENCES AND RESEARCH


Open Access

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ABSTRACT

Title : Anticancer Activity and In-Silico ADMET Analysis of Malvastrum Coromandelianum
Authors : Akshay R. Yadav, Shrinivas K. Mohite
Keywords : Breast cancer, Malvastrum coromandelianum, Anticancer activity, SwissADME.
Issue Date : May 2020
Abstract :
Breast cancer is the world's leading cause of cancer death and the most common cancer among women. There is significant variation in survival rates worldwide for breast cancer, where 80% are estimated to be below 40% for low-income countries in the high income countries for 5 years. Natural products have been considered to be important sources of potential chemotherapeutic agents and many anticancer drugs have originated from different natural sources. Primary aim of the present study was to investigate the possible anticancer mechanism of Malvastrum coromandelianum extract using in-vitro model. Anticancer activity of ethyl acetate extract of Malvastrum coromandelianum was evaluated by tryphan blue exclusion method and ADME analysis was done with the help of SwissADME software. From the observed results the anticancer activity of Malvastrum coromandelianum is could be due to its Phytochemical constituents.
Page(s) : 71-73
ISSN : 0975-9492
Source : Vol. 11, No.05