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ABSTRACT
| Title |
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A study on prescription pattern of drugs used in the treatment of peptic ulcer disease in a tertiary care hospital |
| Authors |
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Sonali Jain H, Dr. Umesh M., Dr. H. P. Nandeesh |
| Keywords |
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Peptic ulcer disease, Prescribing pattern, Drug Related Problem. |
| Issue Date |
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Jun 2019 |
| Abstract |
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Purpose : To study the prescribing pattern of medications used in the management of peptic ulcer disease and to identify the drug related problems. Methods : A prospective interventional study was conducted over a period of nine months in the department of gastroenterology among both in-patients and out-patients, JSS Hospital, Mysuru. Patients diagnosed endoscopically with PUD were enrolled in the study after obtaining inform consent form. Results : A total of 180 PUD patients were included in the study with 108 (60%) out-patients and 72 (40%) in-patients. About 111 (61.66%) participants were started on fixed drug - dose combination therapy for H. pylori eradication followed by PPI maintainance treatment for 42.12±5.94 days. In-patients with complicated PUD (UGIB) were administered with PPI 80mg bolus followed by PPI infusion 8mg/hr for a period of 19.5±6.69 hours. The average cost for managing PUD was found to be approximately in the range of Rs. 4000-5000 (INR). Conclusion: Clarithromycin based H. pylori kit is the prevalent therapy used in H. pylori eradication. The majority of drug related problem encountered was drug-drug interactions followed by sub-therapeutic dose and failure to receive maintainance dose of PPI. |
| Page(s) |
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166-174 |
| ISSN |
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0975-9492 |
| Source |
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Vol. 10, No.6 |
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