ISSN : 0975-9492


Open Access

This website is certified by Health On the Net Foundation. Click to verify.

This site complies with the HONcode standard for trustworthy health information:
verify here.


Title : A study on prescription pattern of drugs used in the treatment of peptic ulcer disease in a tertiary care hospital
Authors : Sonali Jain H, Dr. Umesh M., Dr. H. P. Nandeesh
Keywords : Peptic ulcer disease, Prescribing pattern, Drug Related Problem.
Issue Date : Jun 2019
Abstract :
Purpose : To study the prescribing pattern of medications used in the management of peptic ulcer disease and to identify the drug related problems. Methods : A prospective interventional study was conducted over a period of nine months in the department of gastroenterology among both in-patients and out-patients, JSS Hospital, Mysuru. Patients diagnosed endoscopically with PUD were enrolled in the study after obtaining inform consent form. Results : A total of 180 PUD patients were included in the study with 108 (60%) out-patients and 72 (40%) in-patients. About 111 (61.66%) participants were started on fixed drug - dose combination therapy for H. pylori eradication followed by PPI maintainance treatment for 42.12±5.94 days. In-patients with complicated PUD (UGIB) were administered with PPI 80mg bolus followed by PPI infusion 8mg/hr for a period of 19.5±6.69 hours. The average cost for managing PUD was found to be approximately in the range of Rs. 4000-5000 (INR). Conclusion: Clarithromycin based H. pylori kit is the prevalent therapy used in H. pylori eradication. The majority of drug related problem encountered was drug-drug interactions followed by sub-therapeutic dose and failure to receive maintainance dose of PPI.
Page(s) : 166-174
ISSN : 0975-9492
Source : Vol. 10, No.6