ISSN : 0975-9492
CODEN : IJPSQQ





INTERNATIONAL JOURNAL OF PHARMA SCIENCES AND RESEARCH


Open Access

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ABSTRACT

Title : COMPARTIVE INVESTIGATION OF ANTIMICROBIAL PROPERTIES OF MEDICAL FABRIC COATED WITH AZADIRACHTA INDICA AND ZIZIPHUS JUJUBE
Authors : Dr.B.Senthil Kumar
Keywords : -
Issue Date : Jun 2017
Abstract :
Object: The primary object of this research work is to create the medical fabric to be utilized for hospital wear with antimicrobial properties through natural extracts of azadirchta indica barks and ziziphus jujube leaves. Methods: The dye extracts of Azadirchta indica barks was prepared through aqueous extraction method with the support of acetone and ethonal mixure of 25%(v/v) concentration . Similarly Ziziphus jujube leaves were dried and subjected to percolation process with 70% ethanol at room temperature for 24 h , at pH of 7. Three different dye concentration was prepared using the above extracts such as 10%,20%,30% for dyeing of cotton medical fabric with natural mordant (myrobalan). Results: The color strength (K/S) of the all the dyed samples were good. More specifically the dye extracts of 20% concentration produces higher colour strength such as Azadirchta indica barks extracts yielded 9.74(K/S value ) and Ziziphus jujube leaves extract yielded 11.9(K/S value). The washing, light and rubbing fastness properties of dyed fabrics were also good and 20% of dye concentration produces superior performance against all the fastness properties. The Antimicrobial property is one of the important characteristic of medical fabric ,which has been evaluated against two gram Negative bacteria and two gram positive bacteria such as Pseudomonas aeruginosa, Klebsiella lebeliea, Staphylococcus aureus and Micrococcus mucilaginosis microbes at a controlled environment and it zone inhabitation were analyzed Conclusion: It is inferred that all the samples showed better antimicrobial properties and 20% of dyed samples produces higher zone inhabitation than others. More than 20% of dye concentration increases the dye agglomeration and in turn reduces the dye affinity with the fabric, which may be the reason for minimizing the antimicrobial activity as well as dye ability of the fabric
Page(s) : 125-132
ISSN : 0975-9492
Source : Vol. 8, No.06