ISSN : 0975-9492
CODEN : IJPSQQ





INTERNATIONAL JOURNAL OF PHARMA SCIENCES AND RESEARCH


Open Access

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ABSTRACT

Title : Phytochemical screening and Antioxidant activity of Euphorbia caducifolia extracts
Authors : Kusuma Venumadhav, Kottapalli Seshagirirao
Keywords : Euphorbia caducifolia, Free radical scavenging activity, Phylloclade, Phenolic content, Flavonoids.
Issue Date : May 2017
Abstract :
Purpose: This study was conducted to screen the phytochemical compounds present in the phylloclade of Euphorbia caducifolia Haines and to measure the ability of free radical scavenging activity as an antioxidant. Methods: The collected plant phylloclades were properly dried, powdered and extracted with hexane, methanol, and water. Extracts were tested for phytochemicals, total phenolic and flavonoid content, and antioxidant activities. Results: Carbohydrates, phenols, flavonoids, tannins, glycosides were present in water extract and terpenoids along with phenols and flavonoids in methanol. Hexane contains a maximum of terpenoids and reducing sugars. Water extract showed maximum DPPH· free radical (86±1.5%) and nitric oxide scavenging activities (39.23±4.7%) followed by methanol and hexane due to the presence of phenolic (68.740 ± 0.025 mg of GAE/g) and flavonoid contents (50.04±0.125 mg of RE/g). Conclusion: This study suggests that Euphorbia caducifolia is a promising plant for the therapeutic purposes due to its antioxidant activity of water extract and high contents of terpenoids in methanol and water extracts. A further study of isolation and characterization of active compounds from the plant is necessary to treat various diseases and for multiple applications
Page(s) : 92-96
ISSN : 0975-9492
Source : Vol. 8, No.05