ISSN : 0975-9492
CODEN : IJPSQQ





INTERNATIONAL JOURNAL OF PHARMA SCIENCES AND RESEARCH


Open Access

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ABSTRACT

Title : A Review Report on Newer Advancement in Bioisosteric Replacement in Drug Design
Authors : Yashbir Singh, Shweta Srivastava, RashmiTripathi, Yashasvi Jain
Keywords : Bioisosteres, Biological Properties, Structure Activity Relationship
Issue Date : May 2015
Abstract :
Bioisosteres are major challenge to change a compound with high affinity to a biological lead in to a successful drug. It showes one approach used by the pharmaceutical chemist for the rational modification. The objective of a bioisosteric replacement is to modify a new compound with same biological properties to the original compound and improve the structure activity relationship and purity of the compound also.
Page(s) : 939-947
ISSN : 0975-9492
Source : Vol. 6, No.5