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ABSTRACT
| Title |
: |
FORMULATION AND EVALUATION OF FLOATING TABLETS OF NORFLOXACIN |
| Authors |
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Ms. Jyoti Rathore, Mr. Hitesh Kumar Parmar |
| Keywords |
: |
Floating drug, Bioavailability, Sustain release, Gastric fluid. |
| Issue Date |
: |
January 2015 |
| Abstract |
: |
The oral route is considered as the most promising route of drug delivery. Several approaches have been attempted in the preparation of gastro-retentive drug delivery systems. These include floating systems, swell able and expandable systems, high density systems, bioadhesive systems, altered shape systems, gel forming solution or suspension systems and sachet systems. Various approaches have been followed to encourage gastric retention of an oral dosage form. Floating systems have low bulk density so that they can float on the gastric juice in the stomach. The problem arises when the stomach is completely emptied of gastric fluid. In such a situation, there is nothing to float on. |
| Page(s) |
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23-27 |
| ISSN |
: |
0975-9492 |
| Source |
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Vol. 6, No.1 |
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