ISSN : 0975-9492
CODEN : IJPSQQ





INTERNATIONAL JOURNAL OF PHARMA SCIENCES AND RESEARCH


Open Access

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ABSTRACT

Title : Prevalence and risk factors of HIV infection among infants, born from HIV seropositive mothers, tested by DNA-PCR at yekatit 12 Hospital, Addis Ababa, Ethiopia.
Authors : Hagos Amare, Zerihun Weldesenbet, Ataklti G/Tsadik, Enaniye Ayalew, Rahel Aragaw, Fatuma Hassen, Kassu Desta, Aster Tsegaye
Keywords : HIV/AIDS, Mother to child transmission, breast feeding, traditional birth attendants
Issue Date : November 2014
Abstract :
Background: Since its recognition two decades ago, HIV/AIDS remains a major global challenge. Infants contract the infection from their mother in the womb, during birth and breast feeding. In Ethiopia, limited information is available in relation to mother to child transmission (MCT).
Objective: To determine the prevalence of HIV infection among infants born from HIV seropositive mothers and identify associated risk factors.
Method: Hospital based retrospective record review was employed on 159 infants born from HIV seropositive mothers. Data was collected from the pediatric HIV log book using a structured questionnaire. Data was entered in to excel sheet, cleaned and then exported to STATA and analyzed using appropriate statistical tools.
Result: The study revealed that 32.1% (51/159) of the infants born from HIV seropositive mothers were found to be HIV positive. Majority of the infants were born in health institutions and their birth was attended by health professionals. The rate of HIV transmission was about 3 times higher in those born at home and assisted by traditional birth attendants (TBA) than those born at health institutions and assisted by health professionals (58.5% versus 22,9%; P 0.004). The data also revealed a significant association between HIV infection and feeding practice (p 0.004) which was 45.4% (25/55) in those who practice mixed feeding, 34% (18/53) in those practicing exclusive breast feeding and 15.7% (8/51) among those with replacement feeding.
Conclusion: The vertical transmission rate of 32.1% observed in the present study is quite high and is within the estimated range for Sub saharan African countries.
Page(s) : 851-855
ISSN : 0975-9492
Source : Vol. 5, No.11