ISSN : 0975-9492
CODEN : IJPSQQ





INTERNATIONAL JOURNAL OF PHARMA SCIENCES AND RESEARCH


Open Access

This website is certified by Health On the Net Foundation. Click to verify.

This site complies with the HONcode standard for trustworthy health information:
verify here.

ABSTRACT

Title : INCIDENCE OF PREGNANCY INDUCED HYPERTENSION AND DRUG PRESCRIPTION PATTERN OF ANTIHYPERTENSIVE DRUGS IN PREGNANCY
Authors : MANJUSHA SAJITH, VANDANA NIMBARGI, AMIT MODI, RONAK SUMARIYA, ATMARAM PAWAR
Keywords : -
Issue Date : April 2014
Abstract :
Aim: To determine the frequency and distribution of different types of hypertensive disorders of pregnancy and to assess the drug utilization pattern of antihypertensive drugs in pregnancy. Method: A prospective study was conducted over a period of one year in inpatients of Gynaecology and Obstetrics Department at Bharati Hospital, Pune. Patients diagnosed as hy¬pertensive disorder of pregnancy were taken for primary evaluation. The data regarding demographic details, presenting complaints, gestational age, obstetrics history, diagnosis, blood pressure monitoring, current medications, antihypertensive drugs prescribed were collected and the utilization of antihypertensive drugs in pregnancy was evaluated. Result: A total of 1330 pregnant women visited the OBG department, out of which 104 patients were diagnosed with hypertension. The overall prevalence of hypertensive disorders in pregnancy was 7.8%. The mean maternal age was 23.8 years during the hospital admission. The prevalence of Preeclampsia, gestational hypertension, chronic hypertension, and eclampsia were 5.6 %, 1.5%, 0.15 %, and 0.60 % respectively. Highest incidence of hypertension was occurred in age group of 18-22 years (41.3%) and primigravidae patients (53.8%). A majority of patients 67.3 % were on combination therapy whereas 32.7% were on Monotherapy. Methyldopa was the commonest prescribed antihypertensive as monotherapy (17.3 %) as well as in combination therapy (i.e. 28.8 % with methyldopa and Nifedipine). Conclusion: Our study concluded that the incidence of hypertensive disorders in pregnancy was high. Methyldopa was the commonest prescribed antihypertensive in monotherapy and combination, as it is safest during pregnancy
Page(s) : 163-170
ISSN : 0975-9492
Source : Vol. 5, No.4