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ABSTRACT
| Title |
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COST-EFFECTIVENESS ANALYSIS OF ANTI-DIABETIC THERAPY IN A UNIVERSITY TEACHING HOSPITAL |
| Authors |
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Giwa Abdulganiyu, Tayo Fola |
| Keywords |
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Cost-Effectiveness Analysis, Pharmaco-Economics, Anti-Diabetic Therapy |
| Issue Date |
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March 2014 |
| Abstract |
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Purpose: To conduct cost-effectiveness analysis of anti-diabetic therapy in a University Teaching Hospital in 2010. Methods: A retrospective review of selected case-notes was conducted. World Health Organization Defined Daily Dose Method of evaluating drug use and probability method for potential effectiveness of anti-diabetic therapeutic options from literature analysis was employed in determining cost-effectiveness of each anti-diabetic therapeutic option identified from anti-diabetic drug utilization studies. Sample Size, n=1200. Subjects’ case-notes were selected by systematic random sampling (Sampling Interval = 1). Results: Glibenclamide (N1.76/unit of effectiveness) which was more cost-effective than chlopropamide (N2.97/unit of effectiveness) in the management of moderate hyperglycemia in non-obese Type II Diabetes Mellitus was more frequently prescribed (81.5%). Glibenclamide + Metformin (N7.63/unit of effectiveness) which was more frequently prescribed (92.5%) was not necessarily more cost-effective than Chlopropamide + Metformin (N9.76/unit of effectiveness) in the management of moderate hyperglycemia in obese Type II Diabetes- Mellitus. Biphasic Isophane Insulin (N12.65/unit of effectiveness) which was more cost-effective than soluble insulin + insulin zinc (N30.37/unit of effectiveness) in the management of serve hyperglycemia in non-obese Type II Diabetes Mellitus was less frequently prescribed (42.3%). Biphasic Isophane Insulin + Metformin (N15.91/unit of effectiveness ) which was more cost-effective than soluble insulin + insulin zinc + metformin (N34.45/ unit of effectiveness) in the management of severe hyperglycemia in obese Type II Diabetes Mellitus patients was less frequently prescribed (25%). Conclusions: Prescription of lees cost-effective anti-diabetic drugs was rampant in Hospitals. |
| Page(s) |
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82-91 |
| ISSN |
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0975-9492 |
| Source |
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Vol. 5, No.3 |
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