ISSN : 0975-9492
CODEN : IJPSQQ





INTERNATIONAL JOURNAL OF PHARMA SCIENCES AND RESEARCH


Open Access

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ABSTRACT

Title : SPECTROPHOTOMETRIC DETERMINATION OF PHENOL BY CHARGE-TRANSFER COMPLEXATION
Authors : J. El harti, Y. Rahali, M. O.B. Idrissi, M. Draoui
Keywords : phenol, complex, spectrophotometry, validation, control
Issue Date : January 2014
Abstract :
The phenol is used in pharmaceutical domain as agent of preservation, a rapid and reliable spectrophotometric method was validated for its determination in routine control. This method is based on the formation of a charge transfer complex between phenol and 2,6-dichloroquinone-4-chloroimide (DCQ) in basic medium. This produced a blue product with maximum absorption at 610nm. Beer’s law is obeyed and the calibration curve was linear (r = 0.999) over the range 7.5 10-6M – 7.5 10-5
Page(s) : 10-15
ISSN : 0975-9492
Source : Vol. 5, No.1