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ABSTRACT
Title |
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BIOLOGICAL ACTIVITIES OF OXAZINE AND ITS DERIVATIVES: A REVIEW |
Authors |
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SINDHU T J, SONIA D ARIKKATT, GIRLY VINCENT, MEENA CHANDRAN, BHAT A R, KRISHNAKUMAR K |
Keywords |
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Oxazine, Antimicrobial, Antitubercular, Antitumour. |
Issue Date |
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November 2013 |
Abstract |
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Oxazine derivatives are an important class of heterocycles, which has attracted much synthetic interest due to their wide range of biological activities. Oxazine is a heterocyclic compound can be formally derived from benzene, and its reduction products, by suitable substitution of carbon (and hydrogen) atoms by nitrogen and oxygen. In the last few years oxazine derivatives have proved to be valuable synthetic intermediates and also possess important biological activities like sedative, analgesic, antipyretic, anticonvulsant, antitubercular, antitumour, antimalarial and antimicrobial. In these days, development of drug resistance is a major problem and to overcome this situation, it is necessary to synthesize new classes of compounds. The aim of the article is to review the generalization of the collected data about the synthesis of oxazine derivatives and their activities. We hope that this work will be a definite interest for researchers concerned with azines in generally and oxazines in particular. |
Page(s) |
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134-143 |
ISSN |
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0975-9492 |
Source |
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Vol. 4, No.11 |
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