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ABSTRACT
Title |
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SYTHESIS AND ANTITUBERCULAR ACTIVITY OF SOME TRIAZOLE DERIVATIVES OF PROPYL GALLATE |
Authors |
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Sudeep K. Mandal, Dibyajyoti Saha, Vibhor K. Jain, Bindu Jain |
Keywords |
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- |
Issue Date |
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December 2010 |
Abstract |
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Triazole is a diunsaturated heterocyclic compound contains two nitrogen groups as hetero atoms. In present study an attempt was made to synthesis various derivatives of substituted 1,2,4-triazol-3-yl)benzene-1,2,3-triol and to assess their antitubercular efficiency. The synthesized compounds were subjected to physical characterization and spectral analysis by IR and NMR for structure elucidation. The compounds were than subjected to evaluation of antitubercular activity against bacterial strain M. Tuberculosis H37Rv by MABA method using rifampicin as standard. The results of antitubercular activity shows that compounds S3 and S5 showed equivalent activity when compared with that of standard while rest of the compounds found to be less active than standard. |
Page(s) |
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465-472 |
ISSN |
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0975-9492 |
Source |
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Vol. 1, No.11 |
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