ISSN : 0975-9492
CODEN : IJPSQQ





INTERNATIONAL JOURNAL OF PHARMA SCIENCES AND RESEARCH


Open Access

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ABSTRACT

Title : Ciprofloxacin Resistance in Staphylococcus aureus and Pseudomonas aeruginosa Isolated from Patients in Baghdad
Authors : Mohammed F. AL-Marjani, Kadhim A. Kadhim, Afraa A. Kadhim, Ahmad AB Yosef Kinani
Keywords : Staphylococcus aureus, Pseudomonas aeruginosa, Ciprofloxacin, Resistance
Issue Date : February 2015
Abstract :
Total of 50 isolates of Pseudomonas aeruginosa and 50 isolates of Staphylococcus aureus were collected to detect the gyrA and qnrs among S aureus and Ps. aeruginosa isolates respectively from patients in Baghdad. The susceptibility to different antibiotics was evaluated by disk diffusion method and MICs of ciprofloxacin were determined. Among 50 Pseudomonas aeruginosa isolates, resistance was observed most often to Nalidixic acid (54%), followed by Levofloxacin (38%) and Norfloxacin (36%). The resistance patterns of S. aureus were Levofloxacin ( 20 %) , Norfloxacin ( 16 %) , Ofloxacin ( 18 %) ,Ciprofloxacin ( 16 %), Lomofloxacin ( 14 %) and Nalidixic acid ( 50 %). Pseudomonas aeruginosa isolates had MICs between (2-512) g/ml and S. aureus isolates had MICs between (4-265) g/ml. All S. aureus and Pseudomonas aeruginosa isolates were tested for the presence of the gyrA and qnrS genes by PCR, 36% of S. aureus and 24% of Pseudomonas aeruginosa isolates were positive respectively.
Page(s) : 382-385
ISSN : 0975-9492
Source : Vol. 6, No.2